Amoeba Enigma

Amoeba Enigma is a puzzle game for Android devices. Get it on Google Play or Android Apps.

Privacy Statement

This game does not, nor ever will, collect any data.



Communicable, brain-eating amoebas are on the loose!

Your goal is to move all people from the bottom of the board to the top while avoiding or minimizing contact with invisible amoebas randomly scattered around the board. A level ends when everybody is in the top row or dead. If anybody remains healthy, the level resets with the healthy people at the bottom again. The game ends when nobody is healthy or if your remaining time reaches zero.


Touch or click a person to make that person active (indicated with yellow highlighting). Move the active person by touching adjacent board positions. Alternatively, you can touch and drag, but be very careful because it is easy to “fat finger” a person into an unintended location.

For devices with a keyboard, you can move the active person using the arrow keys, WASD+QEZX, and the number pad keys 1-9 (omit 5).

Game Play

As amoebas are invisible to the naked eye, you must infer their locations. If a person begins showing symptoms, the person came into direct contact with an amoeba or stood adjacent to an infected person. Infected people spread amoebas around the board when they move.

Try to maximize your score, which updates after each level. People who live until the end of the level are worth points: elders (8), men (6), women (4), children (2). An infected person is worth half as many points as the same person uninfected.

Pandemic Puzzle game play
  1. Stethoscope
  2. Remaining time (left, in seconds), and score
  3. Danger (red)/Safe (green) markers
  4. ICU bed locations
  5. Antidote
  6. Obstacle
  7. Masks
  8. Person to move

Use the stethoscope to show you who is infected. It costs 5 seconds of remaining time, but you don’t have to wait for anybody to show symptoms.

Use the “danger” and “safe” markers to annotate board positions. For example, if a person is showing symptoms, that board position is definitely infected. Annotate “danger” so you don’t lose this information after the person moves elsewhere.

1 or 2 ICU beds appear in the top row. These special locations are never infected, and infection via transmission between people never occurs to or from an ICU bed location. When an infected person ends a level on an ICU bed, that person might heal and proceed to the next level. Note that infected people can still perish while on a ICU bed before the level ends.

Acquiring the antidote spares a person from infection 3 times. A person does not retain the benefit of these power-ups after a level concludes, and the antidote’s location might be infected.

Acquiring a mask reduces the probability of spreading amoebas between adjacent people. The probability is lowest when both people have a mask. A mask’s location might be infected.



When you have identified a safe path from a person’s location to the top row, you can choose to move that person directly to the top row instead of being limited to adjacent positions. Click a person to make him or her active, and then click a top row position. If there is an unobstructed, presumably safe path available, you will see it denoted with footprints. Click the “X” to decline; click the check to access the path and move the person to the destination.

“Presumably safe” positions are positions you have annotated as safe (green) and spaces in the top and bottom rows that you have not annotated as dangerous (red). The path is actually safe only to the extent that your annotations are correct. You can spread amoebas quickly with fast-forwarding if you’re not careful.

The path is not random. You will always get the same path for the same board conditions.